Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 3/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27195732 | 1.00 | CACNA1H (0.48) | CACNA1HHRH3CACNA1BHDAC1CHRNB2 | |
| SCHEMBL27195800 | 0.96 | CACNA1H (0.48) | CACNA1HHRH3CACNA1BHDAC1CHRNB2 | |
| SCHEMBL30863474 | 0.87 | ABL1 (0.51) | CACNA1HHRH3CACNA1BHDAC1CHRNB2 | |
| SCHEMBL27195981 | 0.87 | ABL1 (0.51) | CACNA1HHRH3CACNA1BHDAC1CHRNB2 | |
| Hydrochloric Acid SCHEMBL30863454 | 0.84 | CACNA1H (0.43) | CACNA1HHRH3CACNA1BHDAC1CHRNB2 | |
| SCHEMBL27195708 | 0.82 | CACNA1H (0.51) | CACNA1HHRH3CACNA1BHDAC1CHRNB2 | |
| SCHEMBL27195733 | 0.82 | TRPV1 (0.59) | CACNA1HCACNA1BHDAC1LMNASMN1; SMN2 | |
| SCHEMBL27195689 | 0.82 | CACNA1H (0.51) | CACNA1HHRH3CACNA1BHDAC1SMN1; SMN2 | |
| SCHEMBL27195723 | 0.82 | CACNA1H (0.51) | CACNA1HHRH3CACNA1BHDAC1SMN1; SMN2 | |
| SCHEMBL27195729 | 0.81 | CACNA1H (0.52) | CACNA1HHRH3CACNA1BHDAC1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581017-A1 | NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS | Biodol Therapeutics (FR) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024079072-A1 | NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS | BIODOL THERAPEUTICS (FR) | 2024-04-18 | — | — | WO | disclosed |