Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039167 | 1.00 | TDP1 (0.53) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL28997957 | 1.00 | TDP1 (0.53) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL28164497 | 1.00 | TDP1 (0.53) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL29565812 | 1.00 | TDP1 (0.53) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL28997020 | 1.00 | TDP1 (0.53) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL18778561 | 1.00 | TDP1 (0.53) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL28996933 | 1.00 | TDP1 (0.53) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL23606549 | 0.94 | TDP1 (0.61) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL24849943 | 0.94 | TDP1 (0.61) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL20556404 | 0.91 | TDP1 (0.44) | TDP1MAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106977577-A | The synthesis of two class abiraterone derivatives | 湖南师范大学 | 2017-07-25 | — | — | CN | claimed |
| US-9677115-B2 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. (US) | 2017-06-13 | — | — | US | disclosed |
| US-20130252268-A1 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. (US) | 2013-09-26 | — | — | US | disclosed |
| US-8460862-B2 | Enzyme substrates for visualizing acidic organelles | Marker Gene Technologies (US) | 2013-06-11 | — | — | US | disclosed |
| US-20100233744-A1 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. | 2010-09-16 | — | — | US | disclosed |