Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15896161 | 1.00 | ERN1 (0.47) | ERN1LMNAMEN1THRBBLM | |
| SCHEMBL18260175 | 0.76 | FFAR1 (0.36) | ERN1GRM5FFAR1ALDH1A1HPGD | |
| SCHEMBL18260174 | 0.76 | FFAR1 (0.36) | ERN1GRM5FFAR1ALDH1A1HPGD | |
| SCHEMBL2491796 | 0.74 | GRM5 (0.55) | ERN1LMNAMEN1KMT2ATDP1 | |
| SCHEMBL31587369 | 0.74 | MEN1 (0.50) | ERN1LMNAMEN1THRBBLM | |
| SCHEMBL8308042 | 0.73 | CYP3A4 (0.52) | ERN1MEN1KMT2AGRM5FFAR1 | |
| SCHEMBL29001511 | 0.73 | GRM5 (0.41) | ERN1GRM5FFAR1ADK | |
| SCHEMBL19133191 | 0.73 | GRM5 (0.49) | ERN1GRM5FFAR1ALDH1A1TSHR | |
| SCHEMBL31424565 | 0.72 | ERN1 (0.35) | ERN1LMNAMEN1THRBBLM | |
| Charcoal, Activated SCHEMBL31286311 | 0.72 | GRM5 (0.53) | ERN1MEN1KMT2ATDP1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903053-A | Synthesis method and application of diaryl azepine compound | 河南工业大学 | 2024-04-19 | — | — | CN | claimed |
| CN-117903053-A | Synthesis method and application of diaryl azepine compound | 河南工业大学 | 2024-04-19 | — | — | CN | disclosed |