Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 3/20 | 0.79 |
| ▸ | EGFR | P00533 | 8/20 | 0.47 |
| ▸ | KDR | P35968 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31620798 | 1.00 | ENPP1 (0.79) | ENPP1EGFRKDRMAPK1FLT1 | |
| SCHEMBL1015576 | 1.00 | ENPP1 (0.79) | ENPP1EGFRKDRMAPK1FLT1 | |
| SCHEMBL1013051 | 1.00 | ENPP1 (0.79) | ENPP1EGFRKDRMAPK1FLT1 | |
| Hydrochloric Acid SCHEMBL28825385 | 0.99 | ENPP1 (0.77) | ENPP1EGFRKDRMAPK1FLT1 | |
| SCHEMBL4029922 | 0.96 | ENPP1 (0.77) | ENPP1EGFRKDRMAPK1FLT1 | |
| SCHEMBL1013021 | 0.94 | ENPP1 (0.79) | ENPP1EGFRKDRMAPK1FLT1 | |
| SCHEMBL662795 | 0.94 | ENPP1 (0.79) | ENPP1EGFRKDRMAPK1FLT1 | |
| SCHEMBL1012358 | 0.94 | ENPP1 (0.79) | ENPP1EGFRKDRMAPK1FLT1 | |
| SCHEMBL8649615 | 0.90 | ENPP1 (0.86) | ENPP1EGFRKDRFLT1HDAC3 | |
| SCHEMBL16760503 | 0.90 | ENPP1 (0.77) | ENPP1EGFRKDRFLT1FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903068-A | Preparation method of gefitinib | 山东新时代药业有限公司 | 2024-04-19 | — | — | CN | disclosed |