Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 11/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 11/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5678927 | 1.00 | ENPP1 (0.48) | ENPP1KDM4EALDH1A1SMN1; SMN2FGFR4 | |
| Hydrochloric Acid SCHEMBL27988052 | 0.99 | ENPP1 (0.47) | ENPP1KDM4EALDH1A1SMN1; SMN2FGFR4 | |
| SCHEMBL5682691 | 0.94 | ENPP1 (0.48) | ENPP1KDM4EALDH1A1SMN1; SMN2FGFR4 | |
| SCHEMBL30000368 | 0.88 | EGFR (0.45) | ENPP1KDM4EALDH1A1SMN1; SMN2FGFR4 | |
| SCHEMBL30001048 | 0.88 | EGFR (0.45) | ENPP1KDM4EALDH1A1SMN1; SMN2FGFR4 | |
| SCHEMBL30001229 | 0.88 | EGFR (0.45) | ENPP1KDM4EALDH1A1SMN1; SMN2FGFR4 | |
| SCHEMBL6000263 | 0.87 | EGFR (0.46) | ENPP1KDM4EALDH1A1SMN1; SMN2FGFR4 | |
| SCHEMBL30000483 | 0.87 | ENPP1 (0.59) | ENPP1KDM4EALDH1A1SMN1; SMN2FGFR4 | |
| SCHEMBL241727 | 0.86 | EGFR (0.58) | KDM4EALDH1A1SMN1; SMN2FGFR4EGFR | |
| Hydrochloric Acid SCHEMBL8814048 | 0.84 | EGFR (0.56) | KDM4EALDH1A1SMN1; SMN2FGFR4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903068-A | Preparation method of gefitinib | 山东新时代药业有限公司 | 2024-04-19 | — | — | CN | disclosed |