Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 17/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | PRKX | P51817 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21379843 | 1.00 | ADORA2A (0.54) | ADORA2AADORA1ADORA2BNTRK1IGF1R | |
| SCHEMBL30864799 | 0.86 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BNTRK1IGF1R | |
| SCHEMBL21379929 | 0.86 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BNTRK1IGF1R | |
| SCHEMBL30864872 | 0.78 | ADORA2A (0.68) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21379938 | 0.75 | CLK4 (0.46) | ADORA2ANTRK1IGF1RFGFR1LTK | |
| SCHEMBL30864742 | 0.75 | CLK4 (0.46) | ADORA2ANTRK1IGF1RFGFR1LTK | |
| Acetic Acid SCHEMBL21380016 | 0.72 | ADORA2A (0.44) | ADORA2ANTRK1IGF1RFGFR1LTK | |
| Acetic Acid SCHEMBL30864792 | 0.72 | ADORA2A (0.44) | ADORA2ANTRK1IGF1RFGFR1LTK | |
| SCHEMBL30864810 | 0.71 | ADORA2A (0.82) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21380014 | 0.71 | ADORA2A (0.82) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384515-B | Imidazopyrimidines and triazolopyrimidines as A2A/A2B inhibitors | 因赛特公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-117903140-A | Imidazopyrimidines and triazolopyrimidines as A2A/A2B inhibitors | 因赛特公司 | 2024-04-19 | — | — | CN | disclosed |