SCHEMBL30865828

SCHEMBL30865828

Cc1ccc(NC(=O)CCc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 1.00
GSPT1 P15170 14/20 1.00
DDB1 Q16531 9/20 0.65
IKZF3 Q9UKT9 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29225882 1.00 CRBN (1.00) CRBNGSPT1DDB1IKZF3
SCHEMBL1413381 0.87 CRBN (0.77) CRBNGSPT1DDB1IKZF3
SCHEMBL24046558 0.87 CRBN (0.77) CRBNGSPT1DDB1IKZF3
SCHEMBL30865843 0.86 CRBN (0.88) CRBNGSPT1DDB1IKZF3
SCHEMBL30865829 0.86 CRBN (1.00) CRBNGSPT1DDB1IKZF3
SCHEMBL29225896 0.86 CRBN (1.00) CRBNGSPT1DDB1IKZF3
SCHEMBL29225899 0.86 CRBN (0.88) CRBNGSPT1DDB1IKZF3
SCHEMBL30865841 0.84 CRBN (0.73) CRBNGSPT1DDB1IKZF3
SCHEMBL29225891 0.84 CRBN (0.73) CRBNGSPT1DDB1IKZF3
SCHEMBL24046560 0.84 CRBN (0.72) CRBNGSPT1DDB1IKZF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117917402-A Isoindolylamide compound, and pharmaceutical composition and application thereof 暨南大学 2024-04-23 CN disclosed