Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 19/20 | 0.65 |
| ▸ | MAP2K2 | P36507 | 6/20 | 0.55 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.52 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23694156 | 0.89 | MAP2K1 (0.52) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL486396 | 0.87 | MAP2K1 (0.72) | MAP2K1MAP2K2MAP2K5EIF2AK1IDO1 | |
| SCHEMBL486804 | 0.85 | MAP2K1 (0.69) | MAP2K1MAP2K2MAP2K5EIF2AK1IDO1 | |
| SCHEMBL486563 | 0.80 | MAP2K1 (0.69) | MAP2K1MAP2K2MAP2K5EIF2AK1IDO1 | |
| SCHEMBL29425363 | 0.80 | MAP2K1 (0.69) | MAP2K1MAP2K2MAP2K5EIF2AK1IDO1 | |
| SCHEMBL1776312 | 0.79 | MAP2K1 (1.00) | MAP2K1MAP2K2MAP2K5EIF2AK1IDO1 | |
| SCHEMBL23694157 | 0.77 | MAP2K1 (0.44) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL27224626 | 0.77 | CYP2C9 (0.56) | MAP2K1MAP2K2IDO1 | |
| SCHEMBL486665 | 0.76 | MAP2K1 (0.57) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL2362783 | 0.76 | MAP2K1 (0.57) | MAP2K1MAP2K2MAP2K5EIF2AK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4375273-A1 | METHOD FOR PRODUCING ARYLAMIDE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-05-29 | — | — | EP | disclosed |