Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | PPM1B | O75688 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10699873 | 0.80 | NPC1 (0.50) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL13866343 | 0.80 | NPC1 (0.50) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL19047815 | 0.80 | NPC1 (0.50) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL25716677 | 0.79 | NPC1 (0.49) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL20833080 | 0.79 | NPC1 (0.52) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL13866333 | 0.79 | NPC1 (0.49) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL22083988 | 0.79 | NPC1 (0.52) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL18671951 | 0.79 | NPC1 (0.49) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL24739169 | 0.78 | NPC1 (0.48) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL22474965 | 0.78 | NPC1 (0.48) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858711-A | Nucleoside and nucleotide analogs as antiviral agents | 爱莫里大学 | 2024-04-09 | — | — | CN | disclosed |