Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.36 |
| ▸ | USP2 | O75604 | 9/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.36 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.35 |
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27320844 | 1.00 | CDK2 (0.39) | CDK2IP6K1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27318664 | 0.84 | GBA1 (0.44) | CDK2IP6K1USP2MAPK1ALOX15 | |
| SCHEMBL30867196 | 0.84 | GBA1 (0.44) | CDK2IP6K1USP2MAPK1ALOX15 | |
| SCHEMBL30867201 | 0.83 | CDK2 (0.43) | CDK2IP6K1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27320098 | 0.83 | CDK2 (0.43) | CDK2IP6K1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31534052 | 0.81 | CYP1A2 (0.40) | CDK2IP6K1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30867213 | 0.81 | CDK2 (0.41) | CDK2IP6K1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30867169 | 0.76 | TRPV1 (0.39) | CDK2IP6K1TRPV1MEN1KMT2A | |
| SCHEMBL27319209 | 0.73 | GBA1 (0.43) | IP6K1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30867129 | 0.73 | GBA1 (0.43) | IP6K1CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598931-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2025-08-13 | — | — | EP | disclosed |
| CN-119948035-A | Compounds useful for modulating AhR signaling | 捷豹治疗有限公司 | 2025-05-06 | — | — | CN | disclosed |
| WO-2024076300-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-04-11 | — | — | WO | disclosed |