Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 8/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867186 | 0.91 | GBA1 (0.55) | GBA1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL27319390 | 0.91 | GBA1 (0.55) | GBA1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL31534058 | 0.86 | GBA1 (0.49) | GBA1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL27319374 | 0.86 | GBA1 (0.49) | GBA1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL27319347 | 0.85 | GBA1 (0.49) | GBA1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30867184 | 0.85 | GBA1 (0.49) | GBA1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30867198 | 0.85 | GBA1 (0.49) | GBA1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL27319878 | 0.85 | GBA1 (0.49) | GBA1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30867159 | 0.84 | GBA1 (0.48) | GBA1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL27319354 | 0.84 | GBA1 (0.48) | GBA1CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598931-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076300-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-04-11 | — | — | WO | disclosed |