⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10478911 | 0.70 | CA1 (0.46) | — | |
| SCHEMBL3278397 | 0.70 | — | — | |
| SCHEMBL10478906 | 0.70 | CA1 (0.46) | — | |
| SCHEMBL339328 | 0.67 | — | — | |
| SCHEMBL2784628 | 0.67 | — | — | |
| SCHEMBL13787346 | 0.67 | — | — | |
| SCHEMBL8155164 | 0.67 | — | — | |
| SCHEMBL25534 | 0.65 | — | — | |
| Sulfamide SCHEMBL5880 | 0.65 | — | — | |
| Sulfamate SCHEMBL10424181 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020922-B | Preparation method of cyclic sulfonamide compound | 陕西师范大学 | 2022-01-04 | — | — | CN | disclosed |
| CN-112969688-A | Fungicidal nitroaniline substituted pyrazoles | FMC公司 | 2021-06-15 | — | — | CN | disclosed |
| CN-112702913-A | Controlled release formulations for agrochemicals | 拜耳公司 | 2021-04-23 | — | — | CN | disclosed |
| CN-110770232-A | Herbicidally active 3-phenylisoxazoline-5-carboxamides of tetrahydro-and dihydrofurancarboxylic acids and esters | 拜耳公司 | 2020-02-07 | — | — | CN | disclosed |
| US-9125856-B1 | Method of stabilizing human eye tissue | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-09-08 | — | — | US | disclosed |
| US-8466203-B2 | Method of stabilizing human eye tissue by reaction with nitrite and related agents such as nitro compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-06-18 | — | — | US | disclosed |
| US-20100173019-A1 | METHOD OF STABILIZING HUMAN EYE TISSUE BY REACTION WITH NITRITE AND RELATED AGENTS SUCH AS NITRO COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-07-08 | — | — | US | disclosed |
| WO-2008070185-A2 | METHOD OF STABILIZING HUMAN EYE TISSUE BY REACTION WITH NITRITE AND RELATED AGENTS SUCH AS NITRO COMPOUNDS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-06-12 | — | — | WO | disclosed |
| US-20070032537-A1 | 5-Substituted 2h-pyrazole-3-carboxylic acid derivatives as agonists for the acid receptor rup25 for the treatment of dyslipidemia and related diseases | ARENA PHARMACEUTICALS, INC. (US) | 2007-02-08 | — | — | US | disclosed |
| EP-1633351-A1 | 5-SUBSTITUTED 2H-PYRAZOLE-3-CARBOXYLIC ACID DERIVATIVES AS AGONISTS FOR THE NICOTINIC ACID RECEPTOR RUP25 FOR THE TREATMENT OF DYSLIPIDEMIA AND RELATED DISEASES | Arena Pharmaceuticals, Inc. (US) | 2006-03-15 | — | — | EP | disclosed |
| WO-2005011677-A1 | 5-SUBSTITUTED 2H-PYRAZOLE-3-CARBOXYLIC ACID DERIVATIVES AS AGONISTS FOR THE NICOTINIC ACID RECEPTOR RUP25 FOR THE TREATMENT OF DYSLIPIDEMIA AND RELATED DISEASES | ARENA PHARMACEUTICALS, INC. (US) | 2005-02-10 | — | — | WO | disclosed |
| US-5356999-A | Contains an ethylene-propylene copolymer which has been grafted with an unsaturated reactive monomer and thereafter with amines containing sulfonamide units; lubricating oil additive | TEXACO INC. (US) | 1994-10-18 | — | — | US | disclosed |
| US-4496514-A | REACTION INJECTION MOLDING | THE B. F. GOODRICH COMPANY (US) | 1985-01-29 | — | — | US | disclosed |
| US-4400490-A | REACTION INJECTION MOLDING OF A LACTAM AND EPOXY COMPOUND; IMPACT STRENGTH | THE B.F. GOODRICH COMPANY (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0085324-A2 | Nylon compositions and rim process for making same | The B.F. GOODRICH Company (US) | 1983-08-10 | — | — | EP | disclosed |