Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112204 | 0.90 | TSHR (0.63) | TSHRKMT2AMEN1HSD17B10LMNA | |
| SCHEMBL15282755 | 0.87 | TSHR (0.60) | TSHRKMT2AMEN1HSD17B10LMNA | |
| SCHEMBL1709989 | 0.83 | — | — | |
| SCHEMBL1845437 | 0.83 | TSHR (0.55) | TSHRKMT2AMEN1HSD17B10LMNA | |
| SCHEMBL1736007 | 0.81 | TSHR (0.52) | TSHRKMT2AMEN1HSD17B10LMNA | |
| SCHEMBL5414056 | 0.81 | — | — | |
| SCHEMBL10606947 | 0.81 | TSHR (0.52) | TSHRKMT2AMEN1HSD17B10LMNA | |
| SCHEMBL19862693 | 0.81 | — | — | |
| SCHEMBL22345266 | 0.81 | — | — | |
| SCHEMBL12231849 | 0.81 | TSHR (0.52) | TSHRKMT2AMEN1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9783658-B2 | Rubber mixtures containing silicic acid and sulfur-containing additives | LANXESS DEUTSCHLAND GMBH (DE) | 2017-10-10 | — | — | US | disclosed |
| US-9249285-B2 | Rubber blends containing silicic acid and comprising additives containing sulphur | LANXESS DEUTSCHLAND GMBH (DE) | 2016-02-02 | — | — | US | disclosed |
| US-20150166774-A1 | RUBBER BLENDS CONTAINING SILICIC ACID AND COMPRISING ADDITIVES CONTAINING SULPHUR | LANXESS DEUTSCHLAND GMBH (DE) | 2015-06-18 | — | — | US | disclosed |
| US-20140155518-A1 | RUBBER MIXTURES CONTAINING SILICIC ACID AND SULFUR-CONTAINING ADDITIVES | LANXESS DEUTSCHLAND GMBH (DE) | 2014-06-05 | — | — | US | disclosed |
| US-20100234552-A1 | POLYOL COMPOUND, TRANSPARENT MOLDED ARTICLE AND METHOD OF MANUFACTURING TRANSPARENT MOLDED ARTICLE | HOYA CORPORATION (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20060155093-A1 | Polyol compound, transparent molded article and method of manufacturing transparent molded article | HOYA CORPORATION (JP) | 2006-07-13 | — | — | US | disclosed |
| EP-1640394-A1 | POLYOL COMPOUND, TRANSPARENT MOLDED OBJECTS, AND PROCESS FOR PRODUCING TRANSPARENT MOLDED OBJECT | HOYA CORPORATION (JP) | 2006-03-29 | — | — | EP | disclosed |