SCHEMBL30869440

SCHEMBL30869440

c1cc2[nH]ncc2cc1-c1cnc2c(c1)Oc1cc(-c3ccc4[nH]ncc4c3)cnc1N2CCCCN1C[C@H]2C[C@@H]1CO2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 4/20 0.43
KCNH2 Q12809 1/20 0.42
GSK3B P49841 7/20 0.39
DYRK1A Q13627 7/20 0.39
WNT1 P04628 4/20 0.39
USP30 Q70CQ3 1/20 0.37
BRAF P15056 1/20 0.35
KRAS P01116 1/20 0.35
ROCK2 O75116 4/20 0.34
ROCK1 Q13464 4/20 0.34
PTPN11 Q06124 1/20 0.34
CDK5 Q00535 3/20 0.34
DYRK3 O43781 2/20 0.34
CLK2 P49760 2/20 0.34
CLK4 Q9HAZ1 2/20 0.34
CLK1 P49759 2/20 0.34
CLK3 P49761 1/20 0.34
CDK5R1 Q15078 1/20 0.34
DYRK2 Q92630 1/20 0.34
DYRK1B Q9Y463 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869791 1.00 CHRNA7 (0.43) CHRNA7KCNH2GSK3BDYRK1AWNT1
SCHEMBL30869394 0.99 CHRNA7 (0.42) CHRNA7KCNH2GSK3BDYRK1AWNT1
SCHEMBL30869787 0.99 CHRNA7 (0.42) CHRNA7KCNH2GSK3BDYRK1AWNT1
SCHEMBL30869736 0.96 CHRNA7 (0.42) CHRNA7KCNH2GSK3BDYRK1AWNT1
SCHEMBL30869764 0.96 CHRNA7 (0.42) CHRNA7KCNH2GSK3BDYRK1AWNT1
SCHEMBL30869632 0.95 CHRNA7 (0.41) CHRNA7KCNH2GSK3BDYRK1AWNT1
SCHEMBL30869435 0.95 CHRNA7 (0.41) CHRNA7KCNH2GSK3BDYRK1AWNT1
SCHEMBL30869810 0.91 CHRNA7 (0.41) CHRNA7KCNH2GSK3BDYRK1AWNT1
SCHEMBL30869474 0.91 CHRNA7 (0.41) CHRNA7KCNH2GSK3BDYRK1AWNT1
SCHEMBL30869522 0.89 CHRNA7 (0.42) CHRNA7KCNH2GSK3BDYRK1AWNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed