SCHEMBL30869552

SCHEMBL30869552

c1cc2c(cc1-c1ccc3[nH]ncc3c1)Oc1cc(-c3ccc4[nH]ncc4c3)cnc1N2CCCN1CCOCC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 3/20 0.52
MAP4K4 O95819 1/20 0.48
ERBB2 P04626 1/20 0.48
MAPK9 P45984 1/20 0.48
CSNK1D P48730 1/20 0.48
PRKD2 Q9BZL6 1/20 0.48
SLK Q9H2G2 1/20 0.48
ROCK2 O75116 3/20 0.38
ROCK1 Q13464 3/20 0.38
DAPK3 O43293 2/20 0.38
CDK1 P06493 2/20 0.38
CDK2 P24941 2/20 0.38
GSK3B P49841 2/20 0.38
CDK5 Q00535 2/20 0.38
DYRK1A Q13627 2/20 0.38
CDC7 O00311 2/20 0.38
DYRK3 O43781 1/20 0.38
RPS6KB1 P23443 1/20 0.38
MAPK1 P28482 1/20 0.38
AKT1 P31749 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869414 0.98 EGFR (0.50) EGFRMAP4K4ERBB2MAPK9CSNK1D
SCHEMBL30869707 0.93 EGFR (0.54) EGFRMAP4K4ERBB2MAPK9CSNK1D
SCHEMBL30869769 0.93 EGFR (0.53) EGFRMAP4K4ERBB2MAPK9CSNK1D
SCHEMBL30869886 0.92 EGFR (0.46) EGFRMAP4K4ERBB2MAPK9CSNK1D
SCHEMBL30869734 0.92 EGFR (0.55) EGFRMAP4K4ERBB2MAPK9CSNK1D
SCHEMBL30869483 0.90 EGFR (0.47) EGFRMAP4K4ERBB2MAPK9CSNK1D
SCHEMBL30869573 0.90 EGFR (0.53) EGFRMAP4K4ERBB2MAPK9CSNK1D
SCHEMBL30869570 0.89 EGFR (0.52) EGFRMAP4K4ERBB2MAPK9CSNK1D
SCHEMBL30869773 0.88 EGFR (0.45) EGFRMAP4K4ERBB2MAPK9CSNK1D
SCHEMBL30869456 0.86 EGFR (0.53) EGFRMAP4K4ERBB2MAPK9CSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed