SCHEMBL30869728

SCHEMBL30869728

BrCCCCCN1c2ccc(Br)cc2Oc2cc(Br)cnc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 3/20 0.33
AHR P35869 3/20 0.33
HDAC3 O15379 1/20 0.30
TUBB4A P04350 1/20 0.30
TUBB P07437 1/20 0.30
TUBA3C P0DPH7 1/20 0.30
HDAC4 P56524 1/20 0.30
TUBA1B P68363 1/20 0.30
TUBA4A P68366 1/20 0.30
TUBB4B P68371 1/20 0.30
TUBB3 Q13509 1/20 0.30
HDAC1 Q13547 1/20 0.30
TUBB2A Q13885 1/20 0.30
TUBB8 Q3ZCM7 1/20 0.30
TUBA3E Q6PEY2 1/20 0.30
TUBA1A Q71U36 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC10 Q969S8 1/20 0.30
HDAC11 Q96DB2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869692 0.99 PIM1 (0.33) PIM1AHR
SCHEMBL30869602 0.89
SCHEMBL30869521 0.88
SCHEMBL30869544 0.87 AHR (0.34) PIM1AHR
SCHEMBL30869389 0.87 AHR (0.34) PIM1AHR
SCHEMBL30869593 0.85 AHR (0.41) PIM1AHRHDAC3TUBB4ATUBB
SCHEMBL13308132 0.84 AHR (0.42) PIM1AHRHDAC3TUBB4ATUBB
SCHEMBL30869685 0.83
SCHEMBL30869759 0.83 HTT (0.35) PIM1AHR
SCHEMBL30869648 0.83 PIM1 (0.32) PIM1AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed