SCHEMBL30869780

SCHEMBL30869780

c1cc2c(cc1-c1ccc3[nH]ncc3c1)Oc1cc(-c3ccc4[nH]ncc4c3)ccc1N2CCCCCN1C[C@@H]2C[C@H]1CO2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 4/20 0.41
KCNH2 Q12809 1/20 0.41
DYRK1A Q13627 11/20 0.38
GSK3B P49841 10/20 0.38
WNT1 P04628 4/20 0.38
CDK5 Q00535 7/20 0.35
CLK2 P49760 3/20 0.35
CLK4 Q9HAZ1 3/20 0.35
DYRK3 O43781 2/20 0.35
CLK1 P49759 2/20 0.35
DYRK1B Q9Y463 2/20 0.35
CLK3 P49761 1/20 0.35
CDK5R1 Q15078 1/20 0.35
DYRK2 Q92630 1/20 0.35
ROCK1 Q13464 8/20 0.35
ROCK2 O75116 7/20 0.35
DAPK3 O43293 6/20 0.35
AURKB Q96GD4 5/20 0.35
CDK2 P24941 5/20 0.35
CDK1 P06493 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869718 1.00 CHRNA7 (0.41) CHRNA7KCNH2DYRK1AGSK3BWNT1
SCHEMBL30869522 0.99 CHRNA7 (0.42) CHRNA7KCNH2DYRK1AGSK3BWNT1
SCHEMBL30869702 0.99 CHRNA7 (0.42) CHRNA7KCNH2DYRK1AGSK3BWNT1
SCHEMBL30869562 0.94 CHRNA7 (0.43) CHRNA7KCNH2DYRK1AGSK3BWNT1
SCHEMBL30869632 0.93 CHRNA7 (0.41) CHRNA7KCNH2DYRK1AGSK3BWNT1
SCHEMBL30869435 0.93 CHRNA7 (0.41) CHRNA7KCNH2DYRK1AGSK3BWNT1
SCHEMBL30869764 0.92 CHRNA7 (0.42) CHRNA7KCNH2DYRK1AGSK3BWNT1
SCHEMBL30869736 0.92 CHRNA7 (0.42) CHRNA7KCNH2DYRK1AGSK3BWNT1
SCHEMBL30869612 0.89 CHRNA7 (0.40) CHRNA7KCNH2DYRK1AGSK3BWNT1
SCHEMBL30869787 0.89 CHRNA7 (0.42) CHRNA7KCNH2DYRK1AGSK3BWNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed