SCHEMBL30870024

CC[C@H](C)[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](N)C(C)C)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCN)C(=O)N[C@H](C(=O)N[C@H](CCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCN)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@H](C)O)[C@@H](C)O)C(C)(C)S

nearest known ligand 0.48

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK8	P45983	1/20	0.48

▸	MAPK9	P45984	1/20	0.48

▸	MAPK10	P53779	1/20	0.48

▸	IL23R	Q5VWK5	6/20	0.45

▸	KEAP1	Q14145	1/20	0.45

▸	NPY2R	P49146	7/20	0.44

▸	NPY4R	P50391	7/20	0.44

▸	NPY5R	Q15761	7/20	0.44

▸	NPY1R	P25929	5/20	0.44

▸	NTSR2	O95665	1/20	0.43

▸	NTSR1	P30989	1/20	0.43

▸	VIPR1	P32241	1/20	0.43

▸	VIPR2	P41587	1/20	0.43

▸	KISS1R	Q969F8	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30870057	1.00	MAPK8 (0.48)	MAPK8MAPK9MAPK10IL23RKEAP1
SCHEMBL30870038	1.00	MAPK8 (0.48)	MAPK8MAPK9MAPK10IL23RKEAP1
SCHEMBL30870088	1.00	MAPK8 (0.48)	MAPK8MAPK9MAPK10IL23RKEAP1
SCHEMBL30870069	1.00	MAPK8 (0.48)	MAPK8MAPK9MAPK10IL23RKEAP1
SCHEMBL30870087	0.99	MAPK8 (0.48)	MAPK8MAPK9MAPK10IL23RKEAP1
SCHEMBL30870054	0.99	MAPK8 (0.48)	MAPK8MAPK9MAPK10IL23RKEAP1
SCHEMBL30183488	0.99	MAPK8 (0.48)	MAPK8MAPK9MAPK10IL23RKEAP1
SCHEMBL30870005	0.99	MAPK8 (0.48)	MAPK8MAPK9MAPK10IL23RKEAP1
SCHEMBL30183774	0.99	MAPK8 (0.48)	MAPK8MAPK9MAPK10IL23RKEAP1
SCHEMBL30870062	0.99	MAPK8 (0.48)	MAPK8MAPK9MAPK10IL23RKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240228555-A9	ANTIMICROBIAL PEPTIDOMIMETICS	BASILEA PHARMACEUTICA INTERNATIONAL AG, ALLSCHWIL (CH)	2024-07-11	—	—	US	claimed
US-20240132553-A1	ANTIMICROBIAL PEPTIDOMIMETICS	SPEXIS AG (CH)	2024-04-25	—	—	US	claimed
US-20240228555-A9	ANTIMICROBIAL PEPTIDOMIMETICS	BASILEA PHARMACEUTICA INTERNATIONAL AG, ALLSCHWIL (CH)	2024-07-11	—	—	US	disclosed
US-20240132553-A1	ANTIMICROBIAL PEPTIDOMIMETICS	SPEXIS AG (CH)	2024-04-25	—	—	US	disclosed