Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.59 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.59 |
| ▸ | NTSR1 | P30989 | 12/20 | 0.55 |
| ▸ | NTSR2 | O95665 | 11/20 | 0.55 |
| ▸ | SORT1 | Q99523 | 10/20 | 0.54 |
| ▸ | NPY1R | P25929 | 4/20 | 0.53 |
| ▸ | NPY2R | P49146 | 1/20 | 0.53 |
| ▸ | NPY4R | P50391 | 1/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.53 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.50 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30870039 | 0.95 | MAPK8 (0.59) | MAPK8MAPK9MAPK10NTSR1NTSR2 | |
| SCHEMBL30870075 | 0.95 | MAPK8 (0.59) | MAPK8MAPK9MAPK10NTSR1NTSR2 | |
| SCHEMBL30870045 | 0.95 | MAPK8 (0.59) | MAPK8MAPK9MAPK10NTSR1NTSR2 | |
| SCHEMBL30870059 | 0.94 | MAPK8 (0.62) | MAPK8MAPK9MAPK10NTSR1NTSR2 | |
| SCHEMBL30870011 | 0.92 | MAPK8 (0.58) | MAPK8MAPK9MAPK10NTSR1NTSR2 | |
| SCHEMBL30581312 | 0.92 | MAPK8 (0.58) | MAPK8MAPK9MAPK10NTSR1NTSR2 | |
| SCHEMBL30581282 | 0.91 | MAPK8 (0.57) | MAPK8MAPK9MAPK10NTSR1NTSR2 | |
| SCHEMBL30183954 | 0.91 | MAPK8 (0.57) | MAPK8MAPK9MAPK10NTSR1NTSR2 | |
| SCHEMBL30870068 | 0.91 | MAPK8 (0.57) | MAPK8MAPK9MAPK10NTSR1NTSR2 | |
| SCHEMBL30870073 | 0.91 | MAPK8 (0.57) | MAPK8MAPK9MAPK10NTSR1NTSR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228555-A9 | ANTIMICROBIAL PEPTIDOMIMETICS | BASILEA PHARMACEUTICA INTERNATIONAL AG, ALLSCHWIL (CH) | 2024-07-11 | — | — | US | disclosed |
| US-20240132553-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | SPEXIS AG (CH) | 2024-04-25 | — | — | US | disclosed |