Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 6/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.38 |
| ▸ | AXIN2 | Q9Y2T1 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27443951 | 1.00 | PARP1 (0.45) | PARP1PARP3PARP15TNKSTNKS2 | |
| SCHEMBL27437229 | 0.77 | PARP1 (0.58) | PARP1PARP3PARP15TNKSTNKS2 | |
| SCHEMBL27437262 | 0.75 | PARP1 (0.55) | PARP1PARP3PARP15TNKSTNKS2 | |
| SCHEMBL27436689 | 0.75 | PARP1 (0.55) | PARP1PARP3PARP15TNKSTNKS2 | |
| SCHEMBL628360 | 0.71 | TNKS (0.44) | PARP1TNKSTNKS2GAABTK | |
| SCHEMBL7782055 | 0.67 | PARP1 (0.67) | PARP1PARP3PARP15TNKSTNKS2 | |
| SCHEMBL22961412 | 0.64 | BTK (0.54) | GAABTKEPHX2KMT2AL3MBTL1 | |
| SCHEMBL17942077 | 0.64 | EPHX2 (0.45) | GAABTKEPHX2KMT2AL3MBTL1 | |
| SCHEMBL17950141 | 0.64 | GAA (0.47) | GAABTKEPHX2KMT2AL3MBTL1 | |
| SCHEMBL17942105 | 0.64 | EPHX2 (0.45) | GAABTKEPHX2KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024086246-A2 | 2-SUBSTITUTED 3,4 A, 5, 7, 8, 8 A-HEXAHYDRO-4H-THIOP YRANO [4,3- DJPYRIMIDIN-4-ONES FOR WOUND TREATMENT | Eluciderm Inc. (US) | 2024-04-25 | — | — | WO | disclosed |