Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 20/20 | 0.56 |
| ▸ | HCRTR2 | O43614 | 20/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30872175 | 0.90 | HCRTR1 (0.53) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL27108586 | 0.90 | HCRTR2 (0.58) | HCRTR1HCRTR2 | |
| SCHEMBL30872173 | 0.88 | HCRTR1 (0.63) | HCRTR1HCRTR2 | |
| SCHEMBL30997287 | 0.86 | HCRTR1 (0.65) | HCRTR1HCRTR2 | |
| SCHEMBL31351486 | 0.86 | HCRTR1 (0.56) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL30872185 | 0.85 | HCRTR1 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL27108712 | 0.81 | HCRTR1 (0.52) | HCRTR1HCRTR2 | |
| SCHEMBL31351496 | 0.81 | HCRTR1 (0.60) | HCRTR1HCRTR2 | |
| SCHEMBL31351493 | 0.80 | HCRTR1 (0.59) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL30872159 | 0.76 | HCRTR1 (0.63) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4471034-A1 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-C]PYRROLE METHYL KETONE DERIVATIVE AND APPLICATION THEREOF | Jiangsu NHWA Pharmaceutical Co., Ltd (CN) | 2024-12-04 | — | — | EP | disclosed |
| CN-118556061-A | Disubstituted octahydropyrrolo [3,4-c ] pyrrole methyl ketone derivative and application thereof | 江苏恩华药业股份有限公司 | 2024-08-27 | — | — | CN | disclosed |
| WO-2024109672-A1 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-C]PYRROLE METHYL KETONE DERIVATIVE AND APPLICATION THEREOF | 江苏恩华药业股份有限公司 | 2024-05-30 | — | — | WO | disclosed |