Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 19/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30872176 | 0.87 | KDM4E (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL30872171 | 0.86 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL30872186 | 0.85 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL30872184 | 0.84 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL30872174 | 0.83 | HCRTR1 (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL31351492 | 0.83 | HCRTR1 (0.68) | HCRTR1HCRTR2 | |
| SCHEMBL30872180 | 0.83 | HCRTR1 (0.43) | HCRTR1HCRTR2BRD4BRD2BRD3 | |
| SCHEMBL30872177 | 0.75 | HCRTR1 (0.65) | HCRTR1HCRTR2 | |
| SCHEMBL30872162 | 0.73 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL30872157 | 0.72 | HCRTR2 (0.70) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024109672-A1 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-C]PYRROLE METHYL KETONE DERIVATIVE AND APPLICATION THEREOF | 江苏恩华药业股份有限公司 | 2024-05-30 | — | — | WO | disclosed |