Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 12/20 | 0.54 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.53 |
| ▸ | MERTK | Q12866 | 8/20 | 0.52 |
| ▸ | AXL | P30530 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626124 | 0.89 | MERTK (0.67) | TYRO3MERTKAXL | |
| SCHEMBL29626133 | 0.81 | TYRO3 (0.70) | TYRO3ACVRL1MERTKAXL | |
| SCHEMBL19377511 | 0.80 | TYRO3 (0.69) | TYRO3MERTKAXL | |
| SCHEMBL29626170 | 0.80 | TYRO3 (0.69) | TYRO3MERTKAXL | |
| SCHEMBL19377712 | 0.80 | MERTK (0.72) | TYRO3MERTKAXL | |
| SCHEMBL26613641 | 0.78 | MERTK (0.72) | TYRO3MERTKAXL | |
| SCHEMBL29626157 | 0.78 | MERTK (0.71) | TYRO3MERTKAXL | |
| SCHEMBL29626265 | 0.78 | TYRO3 (0.71) | TYRO3MERTKAXL | |
| SCHEMBL29626188 | 0.76 | MERTK (0.72) | TYRO3MERTKAXL | |
| SCHEMBL19398159 | 0.75 | TYRO3 (0.85) | TYRO3MERTKAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4321513-A2 | PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS | Incyte Corporation (US) | 2024-02-14 | — | — | EP | disclosed |