Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.48 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23960525 | 0.87 | MAPT (0.61) | MAPTALDH1A1GAAALOX12L3MBTL1 | |
| SCHEMBL30874694 | 0.86 | MAPT (0.53) | MAPTALDH1A1GAAALOX12L3MBTL1 | |
| SCHEMBL13624250 | 0.84 | MAPT (0.58) | MAPTALDH1A1GAAALOX12L3MBTL1 | |
| SCHEMBL28143501 | 0.82 | MAPT (0.49) | MAPTALDH1A1GAAALOX12L3MBTL1 | |
| SCHEMBL19647423 | 0.79 | F10 (0.53) | — | |
| SCHEMBL4368258 | 0.79 | GAA (0.52) | MAPTALDH1A1GAAALOX12L3MBTL1 | |
| SCHEMBL4368253 | 0.79 | GAA (0.52) | MAPTALDH1A1GAAALOX12L3MBTL1 | |
| SCHEMBL4368142 | 0.78 | GAA (0.62) | MAPTALDH1A1GAAALOX12L3MBTL1 | |
| SCHEMBL14022834 | 0.78 | MAPT (0.58) | MAPTALDH1A1GAAALOX12L3MBTL1 | |
| SCHEMBL4891787 | 0.78 | MAPT (0.58) | MAPTALDH1A1GAAALOX12L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886779-A | Piperazine alcohol compound with chiral hydroxyl, preparation method and medical application thereof | 徐州医科大学 | 2024-04-16 | — | — | CN | disclosed |