Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | CPT2 | P23786 | 1/20 | 0.52 |
| ▸ | CPT1A | P50416 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396861 | 1.00 | HPGD (0.56) | HPGDAKR1C3MEN1KMT2ARAB9A | |
| SCHEMBL17797648 | 0.91 | HPGD (0.51) | HPGDAKR1C3MEN1KMT2ARAB9A | |
| SCHEMBL1393124 | 0.88 | DPP7 (0.56) | HPGDAKR1C3MEN1KMT2ARAB9A | |
| SCHEMBL30561538 | 0.87 | NOTUM (0.56) | HPGDAKR1C3MEN1KMT2ARAB9A | |
| SCHEMBL3895337 | 0.87 | NOTUM (0.56) | HPGDAKR1C3MEN1KMT2ARAB9A | |
| SCHEMBL6399577 | 0.84 | CPT2 (0.52) | HPGDAKR1C3MEN1KMT2ARAB9A | |
| SCHEMBL15975164 | 0.83 | KMT2A (0.52) | HPGDAKR1C3MEN1KMT2ARAB9A | |
| SCHEMBL22145710 | 0.83 | DPP7 (0.54) | HPGDAKR1C3MEN1KMT2ARAB9A | |
| SCHEMBL29805828 | 0.83 | ESR1 (0.65) | HPGDAKR1C3MEN1KMT2ARAB9A | |
| SCHEMBL15686736 | 0.83 | MEN1 (0.52) | HPGDAKR1C3MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117730083-A | Pyrimidine compounds as MAP4K1 inhibitors | 格兰马克专业公司 | 2024-03-19 | — | — | CN | disclosed |