Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 15/20 | 0.62 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.60 |
| ▸ | MET | P08581 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL25950831 | 0.90 | MAP4K1 (0.61) | MAP4K1ALKMETEGFR | |
| SCHEMBL25947622 | 0.90 | MAP4K1 (0.65) | MAP4K1ALKMETEGFR | |
| SCHEMBL30184069 | 0.87 | MAP4K1 (0.77) | MAP4K1ALK | |
| SCHEMBL25338027 | 0.87 | MAP4K1 (0.77) | MAP4K1ALK | |
| SCHEMBL30875675 | 0.87 | MAP4K1 (0.65) | MAP4K1ALKMET | |
| Hydrochloric Acid SCHEMBL29172302 | 0.86 | MAP4K1 (0.64) | MAP4K1ALKMET | |
| SCHEMBL24716379 | 0.86 | MAP4K1 (0.74) | MAP4K1ALKMET | |
| SCHEMBL30875687 | 0.84 | MAP4K1 (0.64) | MAP4K1ALKMET | |
| SCHEMBL30875686 | 0.83 | MAP4K1 (0.65) | MAP4K1ALKMET | |
| SCHEMBL30184165 | 0.80 | MAP4K1 (0.56) | MAP4K1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117730083-A | Pyrimidine compounds as MAP4K1 inhibitors | 格兰马克专业公司 | 2024-03-19 | — | — | CN | disclosed |