SCHEMBL30875835

SCHEMBL30875835

O=C(O)CCNc1n[n+]([O-])c2cc(OC(F)(F)F)ccc2[n+]1[O-]

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.37
FFAR4 Q5NUL3 7/20 0.36
FFAR1 O14842 4/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
CYP2C9 P11712 2/20 0.36
SCN5A Q14524 2/20 0.36
GCGR P47871 6/20 0.36
POLB P06746 1/20 0.34
KMT2A Q03164 1/20 0.34
SIRT5 Q9NXA8 1/20 0.34
CYP3A4 P08684 2/20 0.33
KCNH2 Q12809 2/20 0.33
CACNA1C Q13936 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2C8 P10632 1/20 0.33
GIPR P48546 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25074671 1.00 ABL1 (0.37) ABL1FFAR4FFAR1CA12CA1
SCHEMBL29864682 1.00 ABL1 (0.37) ABL1FFAR4FFAR1CA12CA1
SCHEMBL29864402 0.86 CETP (0.44) CA12CA1CA2CA9CYP2C9
SCHEMBL25074834 0.86 CETP (0.44) CA12CA1CA2CA9CYP2C9
SCHEMBL25211012 0.85 TDP1 (0.48) FFAR1CA12CA1CA2CA9
SCHEMBL25074972 0.82 CA12 (0.40) FFAR1CA12CA1CA2CA9
SCHEMBL29864507 0.82 CA12 (0.40) FFAR1CA12CA1CA2CA9
SCHEMBL29864553 0.81 CA12 (0.33) CA12CA1CA2CA9
SCHEMBL25210259 0.81 TDP1 (0.48) FFAR1CA12CA1CA2CA9
SCHEMBL25418891 0.81 CA12 (0.33) CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114901646-B Benzotriazine bisoxides and pharmaceutical compositions thereof 浙江瑞臻医药有限公司 2024-06-04 CN disclosed