Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11004432 | 0.80 | KDM4E (0.43) | KDM4EACHEBCHEHDAC8SMN1; SMN2 | |
| SCHEMBL1055898 | 0.78 | SMN1; SMN2 (0.52) | KDM4EACHEBCHEHDAC8MEN1 | |
| SCHEMBL11286540 | 0.78 | KDM4E (0.42) | KDM4EACHEBCHEHDAC8SMN1; SMN2 | |
| SCHEMBL2778719 | 0.78 | KDM4E (0.42) | KDM4EACHEBCHEHDAC8MEN1 | |
| SCHEMBL11004427 | 0.78 | KDM4E (0.46) | KDM4EACHEBCHEHDAC8SMN1; SMN2 | |
| SCHEMBL4981749 | 0.78 | KDM4E (0.42) | KDM4EACHEBCHEHDAC8SMN1; SMN2 | |
| SCHEMBL721593 | 0.78 | HDAC8 (0.50) | KDM4EACHEBCHEHDAC8MEN1 | |
| SCHEMBL950597 | 0.78 | KDM4E (0.42) | KDM4EACHEBCHEHDAC8SMN1; SMN2 | |
| SCHEMBL3617515 | 0.77 | KDM4E (0.33) | KDM4E | |
| Iodide SCHEMBL9773070 | 0.77 | KDM4E (0.41) | KDM4EACHEBCHEHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100181535-A1 | THE PHOTOSTABILITY AND/OR CONTROL OF THE FLUORESCENCE INTENSITY OF FLUORESCENT DYES | PICOQUANT GMBH (DE) | 2010-07-22 | — | — | US | disclosed |