Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4B | O94953 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10546070 | 0.76 | CYP19A1 (0.36) | PARP1CYP19A1METBACE1HSF1 | |
| SCHEMBL30877379 | 0.75 | MAPT (0.37) | KMT2APARP1METKDM4CBACE1 | |
| SCHEMBL31618426 | 0.74 | KMT2A (0.43) | KMT2AKEAP1KDM5BKDM4AKDM4B | |
| SCHEMBL18157906 | 0.72 | KMT2A (0.64) | KMT2AKEAP1CYP19A1JMJD6KDM5B | |
| SCHEMBL863223 | 0.69 | ADORA2A (0.42) | PARP1METKDM4CBACE1HSF1 | |
| SCHEMBL21233327 | 0.68 | KDM4C (0.38) | PARP1METKDM4CBACE1HSF1 | |
| SCHEMBL22952405 | 0.68 | KDM4C (0.35) | PARP1METKDM4CBACE1HSF1 | |
| SCHEMBL30877476 | 0.68 | COMT (0.56) | KMT2AHSF1LRRK2KDM4E | |
| SCHEMBL20019709 | 0.67 | PARP1 (0.44) | KMT2APARP1METKDM4CBACE1 | |
| SCHEMBL14401096 | 0.67 | NISCH (0.44) | KMT2AKEAP1CYP19A1JMJD6KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |