Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19644024 | 1.00 | CNR2 (0.50) | CNR2MAPTALDH1A1CA12CA1 | |
| SCHEMBL1571490 | 0.91 | CNR2 (0.50) | CNR2MAPTCA12CA1CA2 | |
| SCHEMBL16636846 | 0.89 | CNR2 (0.51) | CNR2MAPTALDH1A1CA12CA1 | |
| SCHEMBL1571343 | 0.87 | CNR2 (0.43) | CNR2MAPTCA12CA1CA2 | |
| SCHEMBL29407317 | 0.87 | CNR2 (0.43) | CNR2MAPTCA12CA1CA2 | |
| SCHEMBL25307327 | 0.84 | MAPT (0.45) | CNR2MAPTALDH1A1CA12CA1 | |
| SCHEMBL30609120 | 0.84 | CNR2 (0.43) | CNR2MAPTCA12CA1CA2 | |
| SCHEMBL1411474 | 0.84 | CNR2 (0.50) | CNR2MAPTALDH1A1THRBRORC | |
| SCHEMBL30701970 | 0.84 | CNR2 (0.50) | CNR2MAPTALDH1A1THRBRORC | |
| SCHEMBL12205672 | 0.84 | CNR2 (0.56) | CNR2MAPTBACE1TAS2R14PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112165944-B | Imidazopiperazine inhibitors of transcriptional activator proteins | 德州大学系统董事会 | 2024-04-09 | — | — | CN | disclosed |