Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | TERT | O14746 | 3/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | PPARG | P37231 | 3/20 | 0.58 |
| ▸ | PPARD | Q03181 | 3/20 | 0.58 |
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | TOP1 | P11387 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | FABP4 | P15090 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065479 | 1.00 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL11792635 | 1.00 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL11065482 | 1.00 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL15316123 | 1.00 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL28482040 | 0.98 | EPHX2 (0.61) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL1929342 | 0.98 | EPHX2 (0.61) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL1929345 | 0.98 | EPHX2 (0.61) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL23918136 | 0.92 | EPHX2 (0.73) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL8983130 | 0.92 | EPHX2 (0.73) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL4485310 | 0.92 | EPHX2 (0.69) | EPHX2TERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111867587-A | Thioredoxin reductase inhibitors for the treatment of cancer | 信达制药公司 | 2020-10-30 | — | — | CN | disclosed |
| US-PP21289-P3 | Hop plant named ‘HBC 394’ | Hop Breeding Company, L.L.C. (US) | 2010-09-14 | — | — | US | disclosed |
| US-20090193555-P1 | Hop plant named 'HBC 394' | HOP BREEDING COMPANY, LLC | 2009-07-30 | — | — | US | disclosed |
| US-3953377-A | Ethyl-2-trans-4-cis undecadienoate, ethyl-2-trans-4-cis dodecadienoate and ethyl-2-decadienoate perfume compositions | FIRMENICH S.A. (CH) | 1976-04-27 | — | — | US | disclosed |