Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30879112 | 1.00 | KMT2A (0.46) | KMT2AMEN1ALDH1A1PTGS1PTGS2 | |
| SCHEMBL5971112 | 1.00 | KMT2A (0.46) | KMT2AMEN1ALDH1A1PTGS1PTGS2 | |
| SCHEMBL19931347 | 0.94 | KMT2A (0.41) | KMT2AMEN1ALDH1A1PTGS1PTGS2 | |
| SCHEMBL19931345 | 0.94 | KMT2A (0.41) | KMT2AMEN1ALDH1A1PTGS1PTGS2 | |
| SCHEMBL1926988 | 0.85 | KMT2A (0.41) | KMT2APTGS1PTGS2LMNAL3MBTL1 | |
| SCHEMBL1487233 | 0.85 | KMT2A (0.41) | KMT2APTGS1PTGS2LMNAL3MBTL1 | |
| SCHEMBL1927300 | 0.85 | KMT2A (0.41) | KMT2APTGS1PTGS2LMNAL3MBTL1 | |
| SCHEMBL20511574 | 0.85 | KLK7 (0.38) | KMT2AMEN1ALDH1A1PTGS2L3MBTL1 | |
| SCHEMBL21688721 | 0.85 | KLK7 (0.38) | KMT2AMEN1ALDH1A1PTGS2L3MBTL1 | |
| SCHEMBL18651138 | 0.85 | KLK7 (0.38) | KMT2AMEN1ALDH1A1PTGS2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612148-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024094963-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-10 | — | — | WO | disclosed |