SCHEMBL30879664

SCHEMBL30879664

N=C(N)c1ccc(Oc2ccc(-c3nc4ccc(C(=N)N)cc4[nH]3)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PLAU P00749 5/20 0.80
PLG P00747 4/20 0.80
CHEK2 O96017 8/20 0.73
PRSS1 P07477 1/20 0.71
MEN1 O00255 1/20 0.67
THRB P10828 1/20 0.67
KMT2A Q03164 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20912442 0.99 PLAU (0.77) PLAUPLGCHEK2PRSS1MEN1
SCHEMBL5517426 0.92 PLAU (0.83) PLAUPLGPRSS1
SCHEMBL24312880 0.90 PLAU (0.81) PLAUPLGCHEK2PRSS1
SCHEMBL14519390 0.90 PLAU (0.86) PLAUPLGPRSS1
SCHEMBL12348362 0.89 PLAU (0.79) PLAUPLGPRSS1
SCHEMBL14355116 0.89 PLAU (0.83) PLAUPLGCHEK2PRSS1
SCHEMBL14519369 0.86 PLAU (0.74) PLAUPLGCHEK2PRSS1
SCHEMBL13167159 0.86 PLAU (0.71) PLAUPLGCHEK2PRSS1
SCHEMBL14599555 0.85 PLAU (0.77) PLAUPLGCHEK2PRSS1
SCHEMBL20912411 0.84 PLAU (0.91) PLAUPLGCHEK2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107113-A1 MODIFIED CELLS FOR PROGRAMMING EXTRA ENVELOPED VIRUSES (EEVs) AND THEIR USE FOR PRODUCING THE EEVs, THE PROGRAMMED EEVs AND USES THEREOF CALIDI BIOTHERAPEUTICS (NEVADA), INC. (US) 2026-05-21 WO claimed
WO-2026107113-A1 MODIFIED CELLS FOR PROGRAMMING EXTRA ENVELOPED VIRUSES (EEVs) AND THEIR USE FOR PRODUCING THE EEVs, THE PROGRAMMED EEVs AND USES THEREOF CALIDI BIOTHERAPEUTICS (NEVADA), INC. (US) 2026-05-21 WO disclosed
CN-119895035-A Thermostable reverse transcriptase and application thereof 深圳华大生命科学研究院 2025-04-25 CN disclosed
CN-113785053-B Reverse transcriptase with increased enzymatic activity and use thereof 深圳华大生命科学研究院 2024-07-12 CN disclosed
WO-2024092768-A1 THERMOSTABLE REVERSE TRANSCRIPTASE AND USE THEREOF 深圳华大生命科学研究院 2024-05-10 WO disclosed