Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 4/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | ABL2 | P42684 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TEC | P42680 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30879888 | 0.93 | ABL1 (0.46) | BTKEGFRABL1SRCABL2 | |
| SCHEMBL30879889 | 0.90 | BTK (0.50) | BTKEGFRABL1SRCABL2 | |
| SCHEMBL30879840 | 0.90 | BTK (0.50) | BTKEGFRABL1SRCABL2 | |
| SCHEMBL30879847 | 0.90 | BTK (0.50) | BTKEGFRABL1SRCABL2 | |
| SCHEMBL30879843 | 0.85 | ABL1 (0.48) | BTKEGFRABL1SRCABL2 | |
| SCHEMBL30879927 | 0.85 | GRM5 (0.46) | BTKEGFRABL1SRCABL2 | |
| SCHEMBL30879848 | 0.81 | KCNK3 (0.44) | BTKEGFRABL1SRCABL2 | |
| SCHEMBL30879919 | 0.81 | MAPT (0.56) | BTKEGFRGRM5NPC1RAB9A | |
| SCHEMBL4728976 | 0.78 | BTK (0.53) | BTKEGFRGRM5NPC1RAB9A | |
| SCHEMBL4727867 | 0.77 | BTK (0.49) | BTKEGFRGRM5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092222-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D AND RELATED PRODUCTS AND METHODS | ESCIENT PHARMACEUTICALS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |