Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 9/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | MAP2K5 | Q13163 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | STK10 | O94804 | 1/20 | 0.43 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880699 | 0.89 | GAK (0.53) | IRAK4PDGFRARIPK2ABL1KDR | |
| SCHEMBL29186540 | 0.87 | IRAK4 (0.61) | IRAK4PDGFRARETRIPK2ABL1 | |
| SCHEMBL30880495 | 0.82 | GAK (0.53) | IRAK4RIPK2ABL1KDRMAP2K5 | |
| SCHEMBL30880690 | 0.81 | HTT (0.52) | IRAK4RIPK2EGFRGAKCOQ8A | |
| SCHEMBL30880652 | 0.80 | PDGFRA (0.49) | PDGFRARETRIPK2ABL1KDR | |
| SCHEMBL30880528 | 0.80 | GAK (0.53) | IRAK4RIPK2ABL1MAP2K5EGFR | |
| SCHEMBL30880586 | 0.80 | GAK (0.53) | RIPK2ABL1MAPKAPK2GAKEPHB6 | |
| SCHEMBL30880612 | 0.80 | GAK (0.53) | IRAK4RIPK2ABL1PDGFRBPTK6 | |
| SCHEMBL30880630 | 0.80 | MAPK10 (0.51) | PDGFRARIPK2ABL1KDRMAP2K5 | |
| SCHEMBL30880638 | 0.79 | PDGFRA (0.46) | PDGFRARETRIPK2ABL1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078513-A1 | CONDENSED AZINES FOR TREATING CANCER | CHENGDU ANTICANCER BIOSCIENCE , LTD. (CN) | 2024-04-18 | — | — | WO | disclosed |