Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 12/20 | 0.57 |
| ▸ | RIPK2 | O43353 | 7/20 | 0.57 |
| ▸ | COQ8A | Q8NI60 | 7/20 | 0.57 |
| ▸ | NLK | Q9UBE8 | 7/20 | 0.57 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.57 |
| ▸ | STK16 | O75716 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.57 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880525 | 0.89 | GAK (0.58) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL30880616 | 0.87 | GAK (0.73) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL30880591 | 0.83 | GAK (0.59) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL30880678 | 0.79 | GAK (0.65) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL2289246 | 0.79 | GAK (0.65) | GAKRIPK2COQ8ANLKEPHB6 | |
| Hydrochloric Acid SCHEMBL2291538 | 0.78 | GAK (0.64) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL2292717 | 0.78 | GAK (0.60) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL30880631 | 0.77 | GAK (0.56) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL30880508 | 0.75 | GAK (0.59) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL30880574 | 0.74 | GAK (0.58) | GAKRIPK2COQ8ANLKEPHB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078513-A1 | CONDENSED AZINES FOR TREATING CANCER | CHENGDU ANTICANCER BIOSCIENCE , LTD. (CN) | 2024-04-18 | — | — | WO | disclosed |