Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 2/20 | 0.60 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.53 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.52 |
| ▸ | GAK | O14976 | 3/20 | 0.50 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.50 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.50 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.48 |
| ▸ | RAF1 | P04049 | 2/20 | 0.47 |
| ▸ | BRAF | P15056 | 2/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | TTK | P33981 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.45 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880485 | 0.84 | GAK (0.56) | ALKFGFR3KDRTGFBR1GAK | |
| SCHEMBL30880471 | 0.77 | SYK (0.47) | ALKGAKRIPK2COQ8ANLK | |
| SCHEMBL30880616 | 0.75 | GAK (0.73) | ALKGAKRIPK2COQ8ANLK | |
| SCHEMBL30880613 | 0.75 | GAK (0.73) | KDRGAKRIPK2COQ8ANLK | |
| SCHEMBL30880500 | 0.75 | ALK (0.56) | ALKMAPKAPK2GAKRIPK2COQ8A | |
| SCHEMBL30880716 | 0.75 | ALK (0.56) | ALKMAPKAPK2GAKRIPK2COQ8A | |
| SCHEMBL30880611 | 0.75 | ALK (0.56) | ALKMAPKAPK2GAKRIPK2COQ8A | |
| SCHEMBL30880598 | 0.75 | GAK (0.51) | FGFR3KDRMAPKAPK2TGFBR1GAK | |
| SCHEMBL30880608 | 0.74 | GAK (0.50) | KDRMAPKAPK2TGFBR1GAKRIPK2 | |
| SCHEMBL30880668 | 0.74 | GAK (0.50) | MAPKAPK2TGFBR1GAKRIPK2COQ8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078513-A1 | CONDENSED AZINES FOR TREATING CANCER | CHENGDU ANTICANCER BIOSCIENCE , LTD. (CN) | 2024-04-18 | — | — | WO | disclosed |