Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 12/20 | 0.65 |
| ▸ | RIPK2 | O43353 | 8/20 | 0.60 |
| ▸ | NLK | Q9UBE8 | 7/20 | 0.60 |
| ▸ | COQ8A | Q8NI60 | 6/20 | 0.60 |
| ▸ | EPHB6 | O15197 | 2/20 | 0.60 |
| ▸ | ABL1 | P00519 | 2/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.60 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.60 |
| ▸ | EPHA8 | P29322 | 1/20 | 0.60 |
| ▸ | TXK | P42681 | 1/20 | 0.60 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | STK16 | O75716 | 2/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.40 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880519 | 0.93 | GAK (0.59) | GAKRIPK2NLKCOQ8AEPHB6 | |
| SCHEMBL30880597 | 0.89 | GAK (0.55) | GAKRIPK2NLKCOQ8AEPHB6 | |
| SCHEMBL30880531 | 0.89 | GAK (0.58) | GAKRIPK2NLKCOQ8AEPHB6 | |
| SCHEMBL30880707 | 0.89 | GAK (0.58) | GAKRIPK2NLKCOQ8AEPHB6 | |
| SCHEMBL30880482 | 0.89 | GAK (0.50) | GAKRIPK2NLKCOQ8AEPHB6 | |
| SCHEMBL30880567 | 0.87 | GAK (0.63) | GAKRIPK2NLKCOQ8AEPHB6 | |
| SCHEMBL30880706 | 0.86 | GAK (0.80) | GAKRIPK2NLKCOQ8AEPHB6 | |
| SCHEMBL30880499 | 0.86 | GAK (0.57) | GAKRIPK2NLKCOQ8AEPHB6 | |
| SCHEMBL30880564 | 0.86 | GAK (0.57) | GAKRIPK2NLKCOQ8AEPHB6 | |
| SCHEMBL30880737 | 0.86 | GAK (0.57) | GAKRIPK2NLKCOQ8AEPHB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078513-A1 | CONDENSED AZINES FOR TREATING CANCER | CHENGDU ANTICANCER BIOSCIENCE , LTD. (CN) | 2024-04-18 | — | — | WO | disclosed |