Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.40 |
| ▸ | PDE4A | P27815 | 6/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 4/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.37 |
| ▸ | F7 | P08709 | 3/20 | 0.37 |
| ▸ | F3 | P13726 | 3/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4975328 | 1.00 | AKT1 (0.42) | AKT1PIK3CAMTORPDE4DPDE4A | |
| SCHEMBL30880491 | 0.90 | PDE10A (0.40) | AKT1PIK3CAMTORPDE4DPDE4A | |
| SCHEMBL13095986 | 0.87 | GRM5 (0.41) | PDE4DPDE4APDE4BPDE4CEGFR | |
| SCHEMBL13266273 | 0.87 | GRM5 (0.41) | PDE4DPDE4APDE4BPDE4CEGFR | |
| SCHEMBL29186544 | 0.86 | PDE4D (0.41) | PDE4DPDE4APDE4BPDE4CEGFR | |
| SCHEMBL29186563 | 0.86 | PDE4D (0.41) | PDE4DPDE4APDE4BPDE4CEGFR | |
| SCHEMBL29889664 | 0.86 | PDE4D (0.41) | PDE4DPDE4APDE4BPDE4CEGFR | |
| SCHEMBL30050331 | 0.86 | PDE4D (0.41) | PDE4DPDE4APDE4BPDE4CEGFR | |
| SCHEMBL29186527 | 0.86 | PDE4D (0.41) | PDE4DPDE4APDE4BPDE4CEGFR | |
| SCHEMBL30051301 | 0.86 | PDE4D (0.41) | PDE4DPDE4APDE4BPDE4CEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078513-A1 | CONDENSED AZINES FOR TREATING CANCER | CHENGDU ANTICANCER BIOSCIENCE , LTD. (CN) | 2024-04-18 | — | — | WO | disclosed |