Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 15/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 15/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.42 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22551897 | 1.00 | ADORA2A (0.53) | ADORA2AADORA1ADORA2BTGFBR1TGFBR2 | |
| SCHEMBL30880733 | 0.91 | ADORA2A (0.45) | ADORA2AADORA1ADORA2BTGFBR1 | |
| SCHEMBL22579271 | 0.91 | ADORA2A (0.45) | ADORA2AADORA1ADORA2BTGFBR1 | |
| SCHEMBL22551808 | 0.89 | ADORA2A (0.44) | ADORA2AADORA1ADORA2BTGFBR1 | |
| SCHEMBL30880767 | 0.89 | ADORA2A (0.44) | ADORA2AADORA1ADORA2BTGFBR1 | |
| SCHEMBL22551965 | 0.89 | ADORA2A (0.45) | ADORA2AADORA1ADORA2BTGFBR1TGFBR2 | |
| SCHEMBL23774701 | 0.83 | ADORA2A (0.43) | ADORA2AADORA1ADORA2BTGFBR1 | |
| SCHEMBL21722522 | 0.81 | ADORA2A (0.50) | ADORA2AADORA1ADORA2BTGFBR1TGFBR2 | |
| SCHEMBL22552090 | 0.80 | ADORA2A (0.41) | ADORA2AADORA1ADORA2BTGFBR1 | |
| SCHEMBL30880796 | 0.80 | ADORA2A (0.41) | ADORA2AADORA1ADORA2BTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |