Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | HTR6 | P50406 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 5/20 | 0.59 |
| ▸ | CA9 | Q16790 | 5/20 | 0.59 |
| ▸ | CA1 | P00915 | 4/20 | 0.59 |
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | CA4 | P22748 | 2/20 | 0.59 |
| ▸ | AGO2 | Q9UKV8 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 1/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29874079 | 0.94 | TSHR (0.62) | TSHRHTR6LMNACYP2C9MPO | |
| SCHEMBL31108168 | 0.94 | TSHR (0.62) | TSHRHTR6LMNACYP2C9MPO | |
| SCHEMBL678391 | 0.94 | TSHR (0.62) | TSHRHTR6LMNACYP2C9MPO | |
| SCHEMBL2289878 | 0.94 | TSHR (0.62) | TSHRHTR6LMNACYP2C9MPO | |
| SCHEMBL646075 | 0.94 | TSHR (0.62) | TSHRHTR6LMNACYP2C9MPO | |
| SCHEMBL7766922 | 0.94 | TSHR (0.62) | TSHRHTR6LMNACYP2C9MPO | |
| SCHEMBL31212650 | 0.94 | TSHR (0.62) | TSHRHTR6LMNACYP2C9MPO | |
| Potassium Ion SCHEMBL5776427 | 0.94 | TSHR (0.62) | TSHRHTR6LMNACYP2C9MPO | |
| SCHEMBL11316984 | 0.94 | TSHR (0.62) | TSHRHTR6LMNACYP2C9MPO | |
| SCHEMBL28724178 | 0.94 | TSHR (0.62) | TSHRHTR6LMNACYP2C9MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117737716-A | Plating method for silver sintering connection, plating film, substrate for power module, semiconductor element, and semiconductor device | 上村工业株式会社 | 2024-03-22 | — | — | CN | disclosed |