Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.40 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20548929 | 1.00 | JAK3 (0.49) | JAK3NOTUMJAK2HPGDSTTBK1 | |
| SCHEMBL19098142 | 1.00 | JAK3 (0.49) | JAK3NOTUMJAK2HPGDSTTBK1 | |
| SCHEMBL20548838 | 1.00 | JAK3 (0.49) | JAK3NOTUMJAK2HPGDSTTBK1 | |
| SCHEMBL28812137 | 0.76 | JAK3 (0.60) | JAK3NOTUMJAK2TTBK1TTBK2 | |
| SCHEMBL28249736 | 0.76 | JAK3 (0.47) | JAK3NOTUMJAK2TTBK1TTBK2 | |
| SCHEMBL18599351 | 0.75 | JAK3 (0.46) | JAK3NOTUMJAK2HPGDSTTBK1 | |
| SCHEMBL3491733 | 0.75 | JAK3 (0.59) | JAK3NOTUMJAK2CYP2C9 | |
| Hydrochloric Acid SCHEMBL27966051 | 0.75 | JAK3 (0.59) | JAK3NOTUMJAK2TTBK1TTBK2 | |
| SCHEMBL2606612 | 0.75 | JAK3 (0.59) | JAK3NOTUMJAK2CYP2C9 | |
| Hydrochloric Acid SCHEMBL28120811 | 0.73 | JAK3 (0.57) | JAK3NOTUMJAK2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964625-A | Preparation method of high-optical-purity ponatinib intermediate | 安徽万邦医药科技股份有限公司 | 2024-05-03 | — | — | CN | disclosed |