Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 15/20 | 0.82 |
| ▸ | HSP90AB1 | P08238 | 15/20 | 0.82 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.64 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.56 |
| ▸ | EP300 | Q09472 | 1/20 | 0.55 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.55 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | PTPRC | P08575 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29204875 | 1.00 | HSP90AA1 (0.82) | HSP90AA1HSP90AB1HKDC1HSD17B1HSD17B2 | |
| SCHEMBL29204885 | 0.90 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1HSD17B1HSD17B2STAT3 | |
| SCHEMBL29204882 | 0.88 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1HSD17B1HSD17B2 | |
| SCHEMBL18870893 | 0.88 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1HKDC1HSD17B1HSD17B2 | |
| SCHEMBL29204884 | 0.88 | HSP90AA1 (0.77) | HSP90AA1HSP90AB1HKDC1STAT3 | |
| SCHEMBL29204877 | 0.86 | HSP90AA1 (0.72) | HSP90AA1HSP90AB1HKDC1HSD17B1HSD17B2 | |
| SCHEMBL30883291 | 0.86 | HSP90AA1 (0.72) | HSP90AA1HSP90AB1HKDC1HSD17B1HSD17B2 | |
| SCHEMBL30883290 | 0.86 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1HKDC1HSD17B1HSD17B2 | |
| SCHEMBL29204886 | 0.86 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1HKDC1HSD17B1HSD17B2 | |
| SCHEMBL29204883 | 0.85 | HSP90AA1 (0.77) | HSP90AA1HSP90AB1HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117966179-A | N- (3- (2-hydroxynaphthalene-1-yl) -4-hydroxyphenyl) -4-toluenesulfonamide compound and preparation method and application thereof | 安徽理工大学 | 2024-05-03 | — | — | CN | claimed |
| CN-117966179-A | N- (3- (2-hydroxynaphthalene-1-yl) -4-hydroxyphenyl) -4-toluenesulfonamide compound and preparation method and application thereof | 安徽理工大学 | 2024-05-03 | — | — | CN | disclosed |
| CN-117966179-A | N- (3- (2-hydroxynaphthalene-1-yl) -4-hydroxyphenyl) -4-toluenesulfonamide compound and preparation method and application thereof | 安徽理工大学 | 2024-05-03 | — | — | CN | disclosed |
| CN-117966179-A | N- (3- (2-hydroxynaphthalene-1-yl) -4-hydroxyphenyl) -4-toluenesulfonamide compound and preparation method and application thereof | 安徽理工大学 | 2024-05-03 | — | — | CN | disclosed |