Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 13/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23207913 | 0.88 | STING1 (0.62) | STING1PLK4AURKAROCK2NTRK1 | |
| SCHEMBL30195943 | 0.88 | STING1 (0.62) | STING1PLK4AURKAROCK2NTRK1 | |
| SCHEMBL30885407 | 0.85 | STING1 (0.46) | STING1KIF11NTRK1TRPV1 | |
| SCHEMBL23207670 | 0.83 | STING1 (0.48) | STING1KIF11PLK4AURKAROCK2 | |
| SCHEMBL23207669 | 0.81 | STING1 (0.48) | STING1PLK4LYNTRPV1 | |
| SCHEMBL23208029 | 0.80 | STING1 (0.60) | STING1PLK4AURKAROCK2NTRK1 | |
| SCHEMBL30195946 | 0.80 | STING1 (0.60) | STING1PLK4AURKAROCK2NTRK1 | |
| SCHEMBL30885386 | 0.80 | STING1 (0.58) | STING1KIF11TRPV1 | |
| SCHEMBL23207674 | 0.80 | STING1 (0.44) | STING1PLK4AURKAROCK2NTRK1 | |
| SCHEMBL30885376 | 0.80 | STING1 (0.46) | STING1KIF11DYRK1ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756698-A | Urea compound and medical application thereof as STING inhibitor | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |