Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 13/20 | 0.47 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.46 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885419 | 0.96 | STING1 (0.47) | STING1KCNK2KCNK10KIF11ALDH1A1 | |
| SCHEMBL30386163 | 0.91 | STING1 (0.50) | STING1KIF11ALDH1A1NPC1RAB9A | |
| SCHEMBL30885387 | 0.87 | STING1 (0.47) | STING1KIF11ALDH1A1MEN1NPC1 | |
| SCHEMBL30885424 | 0.85 | STING1 (0.47) | STING1KIF11ALDH1A1MEN1NPC1 | |
| SCHEMBL30885385 | 0.85 | STING1 (0.57) | STING1KCNK2KCNK10KIF11ALDH1A1 | |
| SCHEMBL30885389 | 0.85 | STING1 (0.57) | STING1KCNK2KCNK10KIF11ALDH1A1 | |
| SCHEMBL30885437 | 0.84 | STING1 (0.58) | STING1KCNK2KIF11ALDH1A1NPC1 | |
| SCHEMBL30885386 | 0.84 | STING1 (0.58) | STING1KCNK2KIF11ALDH1A1MAPT | |
| SCHEMBL23167399 | 0.81 | STING1 (0.64) | STING1MEN1MAPTHTTRAB9A | |
| SCHEMBL30885448 | 0.81 | STING1 (0.57) | STING1KCNK2KCNK10KIF11TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756698-A | Urea compound and medical application thereof as STING inhibitor | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |