Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GLRA3 | O75311 | 4/20 | 0.41 |
| ▸ | GLRB | P48167 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23779189 | 1.00 | POLB (0.58) | POLBALDH1A1CYP2D6CHRM1KDM4E | |
| SCHEMBL24058299 | 0.89 | POLB (0.57) | POLBALDH1A1CYP2D6CHRM1KDM4E | |
| SCHEMBL24025525 | 0.86 | POLB (0.63) | POLBALDH1A1CYP2D6CHRM1PKM | |
| SCHEMBL24057970 | 0.83 | POLB (0.67) | POLBALDH1A1CYP2D6CHRM1KDM4E | |
| SCHEMBL24058305 | 0.78 | POLB (0.56) | POLBALDH1A1CYP2D6CHRM1KDM4E | |
| SCHEMBL24025480 | 0.76 | CHRM1 (0.61) | POLBALDH1A1CYP2D6CHRM1KDM4E | |
| SCHEMBL24025466 | 0.76 | CHRM1 (0.57) | POLBALDH1A1CYP2D6CHRM1KDM4E | |
| SCHEMBL12751726 | 0.75 | POLB (0.68) | POLBALDH1A1CYP2D6MEN1KMT2A | |
| SCHEMBL23089669 | 0.75 | POLB (0.90) | POLBALDH1A1CYP2D6CHRM1KDM4E | |
| SCHEMBL2977562 | 0.75 | POLB (0.97) | POLBALDH1A1CYP2D6KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112955214-B | Pyridylsulfonamide derivatives, pharmaceutical compositions and uses thereof | 勃林格殷格翰国际有限公司 | 2024-05-07 | — | — | CN | disclosed |