SCHEMBL30886458

SCHEMBL30886458

CC1CCC(c2ccc3sccc3c2)N(C(=O)C(=O)Nc2cnc(N)c3c2COC3)C1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 20/20 0.54
WDR77 Q9BQA1 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25323931 0.87 PRMT5 (0.71) PRMT5WDR77
SCHEMBL31043216 0.87 PRMT5 (0.71) PRMT5WDR77
SCHEMBL25323926 0.87 PRMT5 (0.71) PRMT5WDR77
SCHEMBL30886219 0.86 PRMT5 (0.56) PRMT5WDR77
SCHEMBL30886250 0.85 PRMT5 (0.70) PRMT5WDR77
SCHEMBL30886308 0.84 PRMT5 (0.52) PRMT5WDR77
SCHEMBL30886359 0.84 PRMT5 (0.52) PRMT5WDR77
SCHEMBL30886275 0.84 PRMT5 (0.53) PRMT5WDR77
SCHEMBL30886378 0.83 PRMT5 (0.51) PRMT5WDR77
SCHEMBL30886225 0.83 PRMT5 (0.51) PRMT5WDR77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118047793-A Pyridine derivative and application thereof 成都百裕制药股份有限公司 2024-05-17 CN disclosed