SCHEMBL30889709

SCHEMBL30889709

O=C(O)CCCCN1CCN(c2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)CC1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 19/20 0.55
▸ GSPT1 P15170 3/20 0.47
▸ ESR1 P03372 1/20 0.46
▸ CSNK1A1 P48729 1/20 0.45
▸ IKZF3 Q9UKT9 1/20 0.44
▸ PTK2 Q05397 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30889715 0.99 CRBN (0.54) CRBNGSPT1ESR1CSNK1A1
SCHEMBL30822503 0.94 CRBN (0.58) CRBNGSPT1ESR1CSNK1A1IKZF3
SCHEMBL30822469 0.93 CRBN (0.55) CRBNGSPT1ESR1CSNK1A1IKZF3
SCHEMBL24734976 0.93 CRBN (0.55) CRBNGSPT1ESR1CSNK1A1IKZF3
SCHEMBL27207467 0.93 CRBN (0.55) CRBNGSPT1ESR1CSNK1A1IKZF3
SCHEMBL30822406 0.92 CRBN (0.54) CRBNGSPT1ESR1CSNK1A1IKZF3
SCHEMBL27207449 0.92 CRBN (0.54) CRBNGSPT1ESR1CSNK1A1IKZF3
SCHEMBL24735220 0.92 CRBN (0.54) CRBNGSPT1ESR1CSNK1A1IKZF3
SCHEMBL29841437 0.92 CRBN (0.54) CRBNGSPT1ESR1CSNK1A1IKZF3
SCHEMBL24734973 0.90 CRBN (0.56) CRBNGSPT1ESR1CSNK1A1IKZF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4611901-A1 RET-LDD PROTEIN DEGRADERS Bristol-Myers Squibb Company (US) 2025-09-10 — — EP disclosed
WO-2024097989-A1 RET-LDD PROTEIN DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2024-05-10 — — WO disclosed
Send feedback