SCHEMBL30890842

SCHEMBL30890842

CNc1cc(Oc2ccc(NC(=O)N3CCC(C)(C)C3=O)nc2C)ccn1

nearest known ligand 0.71

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 20/20 0.71
▸ PDGFRA P16234 11/20 0.71
▸ KIT P10721 7/20 0.71
▸ MET P08581 1/20 0.47
▸ PDGFRB P09619 6/20 0.46
▸ CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21425677 1.00 CSF1R (0.71) CSF1RPDGFRAKITMETPDGFRB
SCHEMBL21425516 0.92 CSF1R (0.70) CSF1RPDGFRAKITMETPDGFRB
SCHEMBL27117089 0.90 CSF1R (0.68) CSF1RPDGFRAKITMETPDGFRB
SCHEMBL21425522 0.89 CSF1R (0.67) CSF1RPDGFRAKITMETPDGFRB
SCHEMBL21425523 0.89 CSF1R (0.68) CSF1RPDGFRAKITMETPDGFRB
SCHEMBL21425517 0.88 CSF1R (0.68) CSF1RPDGFRAKITMETPDGFRB
SCHEMBL21425524 0.87 CSF1R (0.66) CSF1RPDGFRAKITMETPDGFRB
SCHEMBL21772030 0.87 CSF1R (0.66) CSF1RPDGFRAKITMETPDGFRB
SCHEMBL21772029 0.85 CSF1R (0.66) CSF1RPDGFRAKITMETPDGFRB
SCHEMBL21425610 0.85 CSF1R (0.78) CSF1RPDGFRAKITMETPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3632907-B1 N-(AZAARYL)CYCLOLACTAM-1-CARBOXAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF ABBISKO THERAPEUTICS CO LTD (CN) 2024-02-28 — — EP disclosed
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