Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 11/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 4/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21772015 | 1.00 | CSF1R (0.46) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 | |
| SCHEMBL21425565 | 0.87 | CSF1R (0.53) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 | |
| SCHEMBL21771990 | 0.86 | CSF1R (0.45) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 | |
| SCHEMBL30086888 | 0.85 | CSF1R (0.39) | CSF1RPDGFRAPDGFRBFLT3KDR | |
| SCHEMBL23888677 | 0.85 | CSF1R (0.39) | CSF1RPDGFRAPDGFRBFLT3KDR | |
| SCHEMBL21425566 | 0.85 | CSF1R (0.51) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 | |
| SCHEMBL16028718 | 0.83 | CSF1R (0.59) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 | |
| SCHEMBL21426333 | 0.83 | CSF1R (0.49) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 | |
| SCHEMBL30890867 | 0.83 | CSF1R (0.49) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 | |
| SCHEMBL21772014 | 0.81 | CSF1R (0.53) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632907-B1 | N-(AZAARYL)CYCLOLACTAM-1-CARBOXAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | ABBISKO THERAPEUTICS CO LTD (CN) | 2024-02-28 | — | — | EP | disclosed |